Nicotine withdrawal symptoms usually peak within the first 3 days of quitting, and last for about 2 weeks. If you make it through those first weeks. Many people find withdrawal symptoms disappear completely after two to four weeks. Quitline is available to help you quit, 8am – 8pm, Monday to Friday. It can be unpleasant, but withdrawal from tobacco is not dangerous. The first week is usually the hardest. After 2 weeks, many withdrawal symptoms will have.